630 research outputs found

    Eksperimentalno ponašanje prototipa matričnog pretvarača izvedenog s novim energetskim modulima

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    This paper describes the design and the solutions adopted for a matrix converter prototype of 10 kW, based on new integrated power modules. The performance of the converter is verified by means of experimental tests.Članak opisuje projekt i rješenja usvojena za prototip 10 kW matričnog pretvarača, izvedenog s novim integriranim energetskim modulima. Svojstva pretvarača provjerena su eksperimentalnim ispitivanjima

    Eksperimentalno ponašanje prototipa matričnog pretvarača izvedenog s novim energetskim modulima

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    This paper describes the design and the solutions adopted for a matrix converter prototype of 10 kW, based on new integrated power modules. The performance of the converter is verified by means of experimental tests.Članak opisuje projekt i rješenja usvojena za prototip 10 kW matričnog pretvarača, izvedenog s novim integriranim energetskim modulima. Svojstva pretvarača provjerena su eksperimentalnim ispitivanjima

    Rotor magnet demagnetisation diagnosis in asymmetrical six-phase surface-mounted AC PMSM drives

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    Multiphase permanent-magnet synchronous machines (PMSMs) are receiving more and more interest in safety-critical modern industries owing to their higher reliability when compared with conventional three-phase PMSMs. Rotor magnets are critical components, which, in case of fault, directly affect the performance of the PMSMs. Thus, monitoring the rotor magnets status is essential to ensure both high level of efficiency and service continuity. The present study focuses on the investigation of a new approach for the detection of rotor magnet demagnetisation in a vector-controlled asymmetrical six-phase surface-mounted AC PMSM. The main contribution of the proposed technique is the assessment of a rotor demagnetisation fault index derived from the fifth and seventh harmonics of the stator voltage space vector evaluated in the α 5–β 5-plane, and already available in the control system platform. The performance of the proposed approach is evaluated using finite element analysis and numerical simulations, both validated by experimental tests

    Behavioral information effects on postural control intrinsic dynamics

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    Esse estudo teve como objetivo examinar possíveis alterações na dinâmica intrínseca de \ud crianças e adultos decorrentes de informações externas na realização de uma tarefa de manutenção da \ud postura ereta. Participaram do estudo dez crianças de 8 anos de idade e dez adultos jovens de ambos os \ud gêneros. Eles permaneceram na posição ereta dentro de uma sala móvel que foi movimentada \ud continuamente para frente e para trás. Os participantes recebiam informação sobre o movimento da sala e \ud eram solicitados a não oscilar ou a oscilar junto com o movimento da mesma. Os resultados mostraram que \ud a manipulação da informação visual induziu oscilação corporal correspondente (dinâmica intrínseca) em \ud crianças e adultos. Informação sobre o movimento da sala e solicitação de uma ação (informação \ud comportamental) alteraram o relacionamento entre informação visual e oscilação corporal. Crianças \ud apresentaram mais dificuldades em alterar a dinâmica intrínseca do que adultos, indicando que elas são \ud mais dependentes da dinâmica intrínseca do que adultos. Esses resultados trazem implicações importantes \ud para a situação de ensino-aprendizagem, pois indica que aprendizagem envolvendo crianças deve ser \ud estruturada propiciando condições mais favoráveis para alterações na dinâmica intrínseca para que os \ud objetivos da mesma sejam alcançados.The purpose of this study was to examine possible changes in the intrinsic dynamics of children and adults resulting from external information in upright stance task. Ten eight-year-old children and ten young adults, both genders, maintained upright position inside a moving room that was continuously moved frontward and backward. Participants were informed about the room movement and they were requested to sway or not sway with the moving room. The results showed that visual manipulation induces correspondent body sway (intrinsic dynamics) in children and adults. Information about the room movement and the request of an action (behavioral information) changed the relation between visual information and body sway. Although it can be changed, children showed more difficulty in changing the intrinsic dynamics than adults, showing that they are more dependent on intrinsic dynamics than adults. These findings bring important implications to learning, suggesting that children's learning opportunities must be structured properly in order to provide condition of intrinsic dynamics changes towards the goals of the task at hand

    Impact of Star Connection Layouts on the Control of Multiphase Induction Motor Drives Under Open-Phase Fault

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    This paper presents a post-fault control algorithm that minimizes the stator Joule losses in multiphase induction machines under an open-phase fault and for different star connection layouts. The key novelty is that the algorithm can be applied to any configuration of a multi n-phase machine, independently of the connection of the neutral points. The latter is analytically derived and is based on the space vector representation of the machine model. Also, it is shown that a low number of neutral points helps to reduce the winding losses in case of an open-phase fault but requires additional control regulators and computational efforts. The theory is applied to an asymmetrical quadruple three-phase induction machine, which is configured to represent five different motor layouts. Finally, experimental results are presented to validate the control algorithm. The optimal solution that is given in the paper can be employed for the control of symmetrical or asymmetrical multiphase machines with different star connection layouts and in any open-phase post-fault operation

    Embodied Language Learning and Cognitive Bootstrapping:Methods and Design Principles

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    Co-development of action, conceptualization and social interaction mutually scaffold and support each other within a virtuous feedback cycle in the development of human language in children. Within this framework, the purpose of this article is to bring together diverse but complementary accounts of research methods that jointly contribute to our understanding of cognitive development and in particular, language acquisition in robots. Thus, we include research pertaining to developmental robotics, cognitive science, psychology, linguistics and neuroscience, as well as practical computer science and engineering. The different studies are not at this stage all connected into a cohesive whole; rather, they are presented to illuminate the need for multiple different approaches that complement each other in the pursuit of understanding cognitive development in robots. Extensive experiments involving the humanoid robot iCub are reported, while human learning relevant to developmental robotics has also contributed useful results. Disparate approaches are brought together via common underlying design principles. Without claiming to model human language acquisition directly, we are nonetheless inspired by analogous development in humans and consequently, our investigations include the parallel co-development of action, conceptualization and social interaction. Though these different approaches need to ultimately be integrated into a coherent, unified body of knowledge, progress is currently also being made by pursuing individual methods

    Lenalidomide in Pretreated Mantle Cell Lymphoma Patients: An Italian Observational Multicenter Retrospective Study in Daily Clinical Practice (the Lenamant Study)

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    Background: Mantle cell lymphoma (MCL) has the worst prognosis of B-cell subtypes owing to its aggressive clinical disease course and incurability with standard chemo-immunotherapy. Options for relapsed MCL are limited, although several single agents have been studied. Lenalidomide is available in Italy for patients with MCL based on a local disposition of the Italian Drug Agency. Subjects, Materials, and Methods: An observational retrospective study was conducted in 24 Italian hematology centers with the aim to improve information on effectiveness and safety of lenalidomide use in real practice. Results: Seventy patients received lenalidomide for 21/28 days with a median of eight cycles. At the end of therapy, there were 22 complete responses (31.4%), 11 partial responses, 6 stable diseases, and 31 progressions, with an overall response rate of 47.1%. Eighteen patients (22.9%) received lenalidomide in combination with either dexamethasone (n = 13) or rituximab (n = 5). Median overall survival (OS) was reached at 33 months and median disease-free survival (DFS) at 20 months: 14/22 patients are in continuous complete response with a median of 26 months. Patients who received lenalidomide alone were compared with patients who received lenalidomide in combination: OS and DFS did not differ. Progression-free survivals are significantly different: at 56 months, 36% in the combination group versus 13% in patients who received lenalidomide alone. Toxicities were manageable, even if 17 of them led to an early drug discontinuation. Conclusion: Lenalidomide therapy for relapsed MCL patients is effective and tolerable even in a real-life context. Implication for Practice: Several factors influence treatment choice in relapsed/refractory mantle cell lymphoma (rrMCL), and the therapeutic scenario is continuously evolving. In fact, rrMCL became the first lymphoma for which four novel agents have been approved: temsirolimus, lenalidomide, ibrutinib, and bortezomib. The rrMCL therapeutic algorithm is not so well established because data in the everyday clinical practice are still poor. Lenalidomide for rrMCL patients is effective and tolerable even in a real-life context

    Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

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    BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London
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